Dr. G. L. Gupta

Interest areas:

• Alzheimer’s disease
• Alcohol addiction
• Chronic Unpredictable Mild Stress
• Preclinical Toxicity studies
• CNS disorders- Psychopharmacology

Awards

• Dr. G. L. Gupta received Travel Grant from the Science & Engineering Research Board (SERB), Govt. of India, for the presentation of his research paper at the 19th World Congress of Basic & Clinical Pharmacology (WCP-2023) organized by British Pharmacological Society and International Union of Pharmacology (IUPHAR) during July 2-7, 2023 at Glasgow, Scotland, United Kingdom.
• Dr. G. L. Gupta was awarded 500 pounds for attending the conference paper at the 19th World Congress of Basic & Clinical Pharmacology (WCP-2023) during July 2-7, 2023 at Glasgow, Scotland, United Kingdom.
• Invited as an expert by Science and Engineering Research Board, Govt. of India to evaluate CRG proposal for financial grant on December 09, 2022.
• Dr. G. L. Gupta received Travel Grant from Science & Engineering Research Board (SERB), Govt. of India for the presentation of his research paper in the 17th Congress of the European Society for Biomedical Research on Alcoholism during September 21-24, 2019 in Lille, France.
• Dr. G. L. Gupta has been awarded for serving as a reviewer for Phytotherapy Research (Wiley, Impact factor: 3.092).
• Dr. G. L. Gupta awarded 650 Euro for registration to the conference 17th Congress of the European Society for Biomedical Research on Alcoholism during September 21-24, 2019 in Lille, France.
• Dr. G. L. Gupta appointed as Bentham Brand Ambassador by Bentham Science for the period of 2019-2020.
• Awarded Foreign Travel Grant from SVKM’s NMIMS, Vile Parle West, Mumbai, to attend the 8^thInternational Conference on “Addictive Disorders and Alcoholism” in Singapore.
• Awarded Travel Grant from Science & Engineering Research Board (SERB), Govt. of India for attending conference “World Congress on Alcohol and Alcoholism” organised jointly by International Society of Biomedical Research on Alcoholism (ISBRA) and the European Society for Biomedical Research on Alcoholism (ESBRA) from September 2-5, 2016 at Berlin, Germany.
• Awarded 500 Euro for registration to the conference “World Congress on Alcohol and Alcoholism” by International Society of Biomedical Research on Alcoholism (ISBRA) and the European Society for Biomedical Research on Alcoholism (ESBRA) organized on September 2-5, 2016 at Berlin, Germany.
• Presented paper in GUFIC PRIZE session in 5th IUPHAR World Conference on the Pharmacology of Natural Products on the Theme: Natural Medicines for Healthy Ageing: from Molecular Targets to Therapy and 51st Annual Conference of Indian Pharmacological Society (IPS) organized during December 5th-7th, 2019 at ICMR- National Institute of Nutrition, Hyderabad, India.
• Received Best Oral Presentation Award in 3rd International conference on “Ethnopharmacology and Evaluation of Medicinal Plants – Global Perspectives”. The award was given by Dr. Rudolf Bauer, President of the International Society for Ethnopharmacology, UK. The conference was organized by Society for Ethnopharmacology from February 19-21, 2016 at Raipur, Chhattisgarh, India.
• Awarded Travel Grant from ICMR, Govt. of India for the research work of M.Pharm. student Ankit Sharma and co-authors to Dr. Sarika Wairker to attend. The 44th Annual Meeting & Exposition of the Controlled Release Society organized by Controlled Release Society, Boston, Massachusetts, U.S.A. July 16 – 19, 2017.
• Young scientist Award, DST, Government of India.
• Awarded AICTE Fellowship for M. Pharm. Research Work
• Worked on the DST sponsored project during M.Pharm.
• Nominated as Main CPCSEA Nominee by Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), Animal Welfare Division, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India for the inspection of the Animal House Facility and to conduct the Institutional Animal Ethics Committee (IAEC) meeting of Directorate of Forensic Science Laboratories, Government of Maharashtra, Mumbai.
• Nominated as Link CPCSEA Nominee by CPCSEA, Animal Welfare Division, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India to the Institutional Animal Ethics Committee (IAEC) of Bharat Serums and Vaccines Ltd, Thane.
• Nominated as Scientist from outside the Institute by CPCSEA, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India as Scientist from outside the Institute to Institutional Animal Ethics Committee (IAEC) of National Institute of Immunohaematology (ICMR), KEM Hospital Campus, Parel, Mumbai, India.
• Nominated as Scientist from outside the Institute by CPCSEA, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India to the Institutional Animal Ethical Committee of Reliance Life Sciences Pvt. Ltd., Navi Mumbai.
• Nominated as Scientist from outside the Institute by CPCSEA, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India to Institutional Animal Ethics Committee (IAEC) of C.U. Shah College of Pharmacy, SNDT Women’s University, Sir Vithaldas Vidya Vihar, Santacruz (W), Mumbai, Maharashtra.
• Nominated as Scientist from outside the Institute by CPCSEA, Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying, Government of India to Institutional Animal Ethics Committee (IAEC) of Haffkine institute of Training, Research & Testing, Parel, Mumbai, Maharashtra.
• Nominated as CPCSEA member by Animal Welfare Division, Ministry of Environment, Forests & Climate Change, Government of India (F.No. 25/197/2013)
• Member Secretary of IAEC at JUIT
• Member of Board of studies in NMIMS University for Pharmacy courses
• Guided Mr. Jaimin Patel, M.Pharm. student on Industry sponsored project from Vaidya Sane Ayurved Lab Ltd., Thane.
• Paper citation in Nature: In the research paper “Wong ML, Arcos-Burgos M, Liu S, Vélez JI, Yu C, Baune BT, Jawahar MC, Arolt V, Dannlowski U, Chuah A, Huttley GA, Fogarty R, Lewis MD, Bornstein SR, Licinio J. ThePHF21Bgeneisassociatedwithmajordepressionandmodulatesthestressresponse. Mol Psychiatry. 2017 Jul;22(7):1015-1025.”
• Invited as a speaker at 8thInternational Conference on Addictive Disorders and Alcoholism” in Singapore.
• Fellowship GATE Examination IIT Madras.
• Invited as a Chairperson for the oral session in the Golden Jubilee Concluding Celebrations&Annual Conference of Indian Pharmacological Society (IPSCON – 2017) Theme: “Integrating Pharmacology with Modern Healthcare” Organized by Indian Pharmacological Society In association with SPPSPTM SVKM’s NMIMS during 15-17 February 2018 at SVKM’s NMIMS, Vile Parle West, Mumbai, 400056, Maharashtra.

Projects/Grants:

Government funded projects as Principal Investigator– SERB: 22 Lakhs, ICMR: 21.16 Lakhs

Seed Grant project as Principal Investigator – 1.00 Lakh

International Travel Grants (Abroad)– 04 (Berlin, Germany; Lille, France; Singapore; Glasgow, Scotland, UK)

Total Number of Publications: 64

Publications and citations:

https://scholar.google.co.in/citations?user=22DNBjIAAAAJ&hl=en

Recent Publications: (Last three years)

1. Pasupalak JK, Rajput P, Gupta GL. Gut microbiota and Alzheimer’s disease: Exploring natural product intervention and the Gut-Brain axis for therapeutic strategies. Eur J Pharmacol. 2024;984:177022. doi:10.1016/j.ejphar.2024.177022. (Elsevier, Impact Factor: 4.2)
2. Raval H, Bhattacharya S, Bhirud D, Sangave PC, Gupta GL, Paraskar G, Jha M, Sharma S, Belemkar S, Kumar D, Maheshwari R. Fabrication of lactoferrin-chitosan-etoposide nanoparticles with melatonin via carbodiimide coupling: In-vitro & in-vivo evaluation for colon cancer. J Control Release. 2024 Dec 3:S0168-3659(24)00836-8. doi:10.1016/j.jconrel.2024.11.077. (Elsevier, Impact Factor: 10.5)
3. Bhirud D, Bhattacharya S, Raval H, Sangave PC, Gupta GL, Paraskar G, Jha M, Sharma S, Belemkar S, Kumar D, Maheshwari R, Sharma M. Chitosan nanoparticles of imatinib mesylate coated with TPGS for the treatment of colon cancer: In-vivo & in-vitro studies. Carbohydr Polym. 2025;348(Pt B):122935. doi:10.1016/j.carbpol.2024.122935. (Elsevier, Impact Factor: 10.7)
4. Pingale TD, Gupta GL. Oleanolic acid-based therapeutics ameliorate motor and depressive behaviors in parkinsonian mice via controlling neuroinflammation and activating Nrf2-BDNF-dopaminergic signaling pathways. Toxicol Mech Methods. 2023. doi:10.1080/15376516.2023.2288198. (Taylor & Francis, Impact Factor: 3.58)
5. Bhattacharya S, Paraskar G, Jha M, Gupta GL, Prajapati BG. Deciphering regulatory T-cell dynamics in cancer immunotherapy: Mechanisms, implications, and therapeutic innovations. ACS Pharmacol Transl Sci. 2024;7(8):2215–2236. doi:10.1021/acsptsci.4c00156. (American Chemical Society, Impact Factor: 4.9)
6. Shah D, Bhattacharya S, Gupta GL, Hatware KV, Jain A, Manthalkar L, Phatak N, Sreelaya P. d-α-tocopheryl polyethylene glycol 1000 succinate surface scaffold polysarcosine-based polymeric nanoparticles of enzalutamide for the treatment of colorectal cancer: In vitro, in vivo characterizations. Heliyon. 2024;10(3):e25172. doi:10.1016/j.heliyon.2024.e25172. (Cell Press, Impact Factor: 4)
7. Sharma V, Gupta GL, Sharma M. Oxidative coupling assembly-induced bio-engineered quercetin microspheres for the gastrosparing delivery of diclofenac sodium. Curr Drug Deliv. 2024;21(4):582-591. doi:10.2174/1567201820666230308100040. (Bentham, Impact Factor: 3.758)
8. Pingale TD, Gupta GL. Acute & sub-acute toxicity study reveals no dentrimental effect of formononetin in mice upon repeated i.p. dosing. Toxicol Mech Methods. 2023;1-17. doi:10.1080/15376516.2023.2234026. (Taylor & Francis, Impact Factor: 4.019)
9. Bhattacharya S, Parihar VK, Singh N, Hatware K, Page A, Sharma M, Prajapati MK, Kanugo A, Pawde D, Maru S, Gupta GL, Kanvinde S. Targeted delivery of panitumumab-scaffold bosutinib-encapsulated polycaprolactone nanoparticles for EGFR-overexpressed colorectal cancer. Nanomedicine (Lond). 2023 Apr;18(9):713-741. doi: 10.2217/nnm-2022-0240. Epub 2023 Jun 13. (Future Medicine, Impact Factor: 6.096)
10. Samant NP, Gupta GL. Acute and Sub-Acute Oral Toxicity Evaluation of Avicularin. Journal of Medicinal and Chemical Sciences 2023;6:2327-2337. (Sami Publishing Company, Impact Factor: 1.71)
11. Dhiman S, Kaur A, Gupta GL, Sharma M. Development and Evaluation of Biotin Functionalized Fullerenes for the Delivery of Irinotecan to Colon Tumors. Curr Drug Deliv. 2023;20(7):978-991. doi: 10.2174/1567201819666220516153010. (Bentham, Impact Factor: 3.758)
12. Shinu P, Gupta GL, Sharma M, et al. Pharmacological Features of 18β-Glycyrrhetinic Acid: A Pentacyclic Triterpenoid of Therapeutic Potential. Plants (Basel). 2023 Mar 1;12(5):1086. doi: 10.3390/plants12051086. (MDPI, Impact Factor: 4.5)
13. Sharma V, Gupta GL, Sharma M. Oxidative coupling assembly induced bio-engineered quercetin microspheres for the gastrosparing delivery of diclofenac sodium. Curr Drug Deliv. 2023 Mar 8. doi: 10.2174/1567201820666230308100040. (Bentham, Impact Factor: 3.758)
14. Gupta GL, Sharma L, Sharma M. 18β-Glycyrrhetinic Acid Ameliorates Neuroinflammation Linked Depressive Behavior Instigated by Chronic Unpredictable Mild Stress via Triggering BDNF/TrkB Signaling Pathway in Rats. Neurochem Res. 2023 Feb;48(2):551-569. doi: 10.1007/s11064-022-03779-7. Epub 2022 Oct 28. PMID: 36307572; PMCID: PMC9616426. (Springer Nature, Impact Factor: 4.414).
15. Shinu P, Sharma M, Gupta GL, et al. Computational Design, Synthesis, and Pharmacological Evaluation of Naproxen-Guaiacol Chimera for Gastro-Sparing Anti-Inflammatory Response by Selective COX2 Inhibition. Molecules. 2022;27(20):6905. . (MDPI, Impact Factor: 4.927).
16. Changotra H, Kaur S, Yadav SS, Gupta GL, Parkash J, Duseja A. ATG5: A central autophagy regulator implicated in various human diseases. Cell Biochem Funct. 2022;40(7):650-667. (Wiley, Impact Factor: 3.963).
17. Samant NP, Gupta GL. Gossypetin- based therapeutics for cognitive dysfunction in chronic unpredictable stress- exposed mice. Metab Brain Dis. 2022;37(5):1527-1539. (Springer Nature, Impact Factor: 3.655).
18. Samant NP, Gupta GL. Avicularin Attenuates Memory Impairment in Rats with Amyloid Beta-Induced Alzheimer’s Disease. Neurotox Res. 2022;40(1):140-153. (Springer Nature, Impact Factor: 3.978).
19. Gupta GL, Samant NP. Current druggable targets for therapeutic control of Alzheimer’s disease. Contemporary Clinical Trials 2021; 109:106549. (Elsevier, Impact Factor: 2.226).
20. Samant NP, Gupta GL. Adiponectin: a potential target for obesity-associated Alzheimer’s disease. Metab Brain Dis. 2021 May 28. doi: 10.1007/s11011-021-00756-x (Springer Nature, Impact Factor: 3.655).
21. Pingale TD, Gupta GL. Novel therapeutic approaches for Parkinson’s disease by targeting brain cholesterol homeostasis. J Pharm Pharmacol. 2021 Jun 8;73(7):862-873. (Wiley, Impact Factor: 3.765).
22. Sharma L, Sharma A, Dash AK, Bisht GS, Gupta GL. A standardized polyherbal preparation POL-6 diminishes alcohol withdrawal anxiety by regulating Gabra1, Gabra2, Gabra3, Gabra4, Gabra5 gene expression of GABAA receptor signaling pathway in rats. BMC Complementary Medicine and Therapies 2021; 21(1):13. (Springer, Impact Factor: 2.986).
23. Pingale T, Gupta GL. Current and emerging therapeutic targets for Parkinson’s disease. Metabolic Brain Disease 2021; 36, 13–27. (Springer Nature, Impact Factor: 3.655).
24. Samant NP, Gupta GL. Novel therapeutic strategies for Alzheimer’s disease targeting brain cholesterol homeostasis. European Journal of Neuroscience 2021; 53(2):673-686. (Wiley, Impact Factor: 3.386).

Book Published: 01

• https://www.amazon.in/Winning-Attitude-NEETU-GUPTA-DR-ebook/dp/B09THYRJ26/ref=sr_1_1?crid=33EN3NJO11IK8&keywords=winning+attitude+gupta&qid=1652621881&sprefix=winning+attitude+gupta%2Caps%2C354&sr=8-1

Book Chapters: 08

• https://doi.org/10.1016/B978-0-12-817933-8.00027-X
• https://doi.org/10.1016/B978-0-12-817933-8.00008-6
• https://doi.org/10.1016/B978-0-12-817935-2.00001-5
• https://doi.org/10.1016/B978-0-443-21800-2.00011-7
• https://doi.org/10.1016/B978-0-443-21800-2.00019-1
• https://doi.org/10.1016/B978-0-323-95696-3.00002-8
• https://link.springer.com/chapter/10.1007/978-981-97-3001-8_8
• https://link.springer.com/referenceworkentry/10.1007/978-3-031-32035-4_36-1

International Conference presentations (Abroad):

• 19th World Congress of Basic & Clinical Pharmacology (WCP-2023) organized by British Pharmacological Society and International Union of Pharmacology (IUPHAR) during July 2-7, 2023 at Glasgow, Scotland, United Kingdom.
• Congress of the European Society for Biomedical Research on Alcoholism, at Lille, France in September, 2019.
• World conference on research integrity at University of Hong Kong, Hong Kong in June, 2019.
• International Conference on “Addictive Disorders and Alcoholism” at Singapore in May, 2018.
• World Congress of Basic and Clinical Pharmacology (WCP2018) at Kyoto International Conference Centre, Kyoto, Japan in July, 2018.
• Annual Meeting & Exposition of the Controlled Release Society at Boston, Massachusetts, U.S.A. in July, 2017.
• “World Congress on Alcohol and Alcoholism” organized jointly by International Society of Biomedical Research on Alcoholism (ISBRA) and the European Society for Biomedical Research on Alcoholism (ESBRA) at Berlin, Germany in September, 2016.

Conferences/Workshops/Seminars:

Presentations: 51

Conferences/Workshops/Seminars attended: 52

Professional memberships:

Life Member of

• Society for Ethnopharmacology (SFE), Affiliated to the International Society for Ethnopharmacology, UK. (SFE/15/I-685)
• Indian Pharmacological Society (IPS)- (LG-307)
• Association of Pharmaceutical Teachers of India (APTI)- (RA/LM-064)
• Indian Pharmacy Graduates’ Association (IPGA)- (LM-5583)
• Society of Toxicology (STOX), India (1073-L)
• The Indian Pharmaceutical Association (IPA) Life Member (MAH/BOM/LM/1506)
• American Society for Pharmacology and Experimental Therapeutics (ASPET) Member (61868)

Editorial Board Member of

• Journal of Alcoholism Clinical Research
• International Journal of Pharmacognosy & Chinese Medicine
• Austin Journal of Pharmacology & Therapeutics
• International Journal of Pharmaceutical Sciences and Drug Research
• Journal of Pharmacology Studies Open Access
• International Journal of Pharmacognosy & Chinese Medicine
• International Journal of Pharmacy and Chemistry
• Journal of Modern Pharmacology and Pathology

Reviewer for the following selected Journals:

• Brain, Behavior, and Immunity (Impact factor: 19.227) published by Elsevier.
• The FASEB Journal (Impact factor: 5.834) published by the Federation of American Societies for Experimental Biology.
• Journal of Affective Disorders (Impact factor: 6.533).
• Frontiers in Pharmacology (Impact factor: 5.988)
• Phytomedicine (Impact factor: 6.656) Elsevier.
• Phytotherapy Research (Impact factor: 6.388) Wiley.
• Psychopharmacology (Impact factor: 4.415) published by Springer.
• Progress in Neuropsychopharmacology & Biological Psychiatry (Impact factor: 5.067) published by Elsevier.
• Neurotoxicity Research (Impact factor: 3.978)
• Neuroscience (Impact factor: 3.244) published by Elsevier.
• Behavioural Brain Research (Elsevier, Impact factor: 3.352).
• Alcohol and Alcoholism (Oxford University Press, Impact factor: 3.913).
• Evidence-Based Complementary and Alternative Medicine (Impact factor: 2.629).
• Chinese Herbal Medicines published by Elsevier.
• BMC Complementary and Alternative Medicine, Springer Nature
• Pharmaceutical Biology (Impact Factor: 3.889) published by Taylor & Francis.

Academic activities

• He has guided 16 M. Pharm. students for their research projects.
• One Ph.D. scholar has been awarded degree and Two Ph.D. scholars are currently registered under his supervision.

Official Email ID: girdharilal.gupta@nmims.edu
Official Phone No.: +91-2563-295545 (Ext:131123)